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Alongside this, there has been increasing recognition of the multi-organ dysfunction (MOD) associated with CP, in particular in children with higher levels of motor impairment.

Our understanding of the underlying cause of CP has developed significantly, with areas such as inflammation, epigenetics and genetic susceptibility to subsequent insults providing new insights. Each case requires detailed consideration of etiology. CP is an umbrella term for a heterogenous condition and is, therefore, descriptive rather than a diagnosis.

11Department of Neonatology, The Coombe Women and Infants University Hospital, Dublin, IrelandĬerebral Palsy (CP) describes a heterogenous group of non-progressive disorders of posture or movement, causing activity limitation, due to a lesion in the developing brain.

10Department of Paediatrics, Cork University Hospital, Cork, Ireland.

9Central Remedial Clinic, Dublin, Ireland.

8Children's Health Ireland at Temple St.

7Children's Health Ireland at Crumlin, Dublin, Ireland.

6Royal College of Surgeons in Ireland, Dublin, Ireland.

5Department of Clinical Genetics, Birmingham Women's Hospital, Birmingham, United Kingdom.

3Children's Health Ireland (CHI) at Tallaght, Dublin, Ireland.

2Trinity Research in Childhood Centre, Trinity College Dublin, Dublin, Ireland.

1Discipline of Pediatrics, School of Medicine, Trinity College Dublin, The University of Dublin, Dublin, Ireland.

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